About this item
The 145-2C11 antibody is specific for mouse CD3e, also known as CD3 epsilon, a 20 kDa subunit of the T cell receptor complex, along with CD3 gamma and CD3 delta. These integral membrane protein chains assemble with additional chains of the T cell receptor (TCR), as well as CD3 zeta chain, to form the T cell receptor – CD3 complex. Together with co-receptors CD4 or CD8, the complex serves to recognize antigens bound to MHC molecules on antigen-presenting cells. Such interactions promote T cell receptor signaling (T cell activation) and can result in a number of cellular responses including proliferation, differentiation, production of cytokines or activation-induced cell death. CD3 is differentially expressed during thymocyte-to-T cell development and on all mature T cells.
The 145-2C11 antibody is a widely used phenotypic marker for mouse T cells. In addition, binding of 145-2C11 antibody to CD3e can induce cell activation (use format . A recent publication of the crystal structure of a murine CD3e-mitogenic antibody complex provides further insight into the action of commonly used agonist antibodies (Fernandes, R.A. et al. 2012. J. Biol. Chem. 287: 13324-13335).
Type: Primary
Antigen: CD3E (CD3e molecule, epsilon (CD3-TCR complex))
Clonality: monoclonal
Clone: 145-2C11
Conjugation: FITC (Fluorescein)
Epitope:
Host: Armenian Hamster
Isotype: IgG
Reactivity: Mouse
Specifications
- Catalog No:
- 35-0031-U100
- 35-0031-U500
- 35-0031-U025
- Antigen symbol:
- CD3E
- CD3E
- CD3E
- Antigen name:
- CD3 Molecule Epsilon
- CD3 Molecule Epsilon
- CD3 Molecule Epsilon
- Antigen synonyms:
- CD3e antigen|TCRE|epsilon subunit of T3|epsilon polypeptide TiT3 complex|T3E|FLJ18683|CD3-epsilon|T-cell surface glycoprotein CD3 epsilon chain|T-cell antigen receptor complex|T-cell surface antigen T3/Leu-4 epsilon chain
- CD3e antigen|TCRE|epsilon subunit of T3|epsilon polypeptide TiT3 complex|T3E|FLJ18683|CD3-epsilon|T-cell surface glycoprotein CD3 epsilon chain|T-cell antigen receptor complex|T-cell surface antigen T3/Leu-4 epsilon chain
- CD3e antigen|TCRE|epsilon subunit of T3|epsilon polypeptide TiT3 complex|T3E|FLJ18683|CD3-epsilon|T-cell surface glycoprotein CD3 epsilon chain|T-cell antigen receptor complex|T-cell surface antigen T3/Leu-4 epsilon chain
- Antibody type:
- Primary
- Primary
- Primary
- Clonality:
- Monoclonal
- Monoclonal
- Monoclonal
- Conjugation:
- FITC (Fluorescein Isothiocyanate)
- FITC (Fluorescein Isothiocyanate)
- FITC (Fluorescein Isothiocyanate)
- Clone:
- 145-2C11
- 145-2C11
- 145-2C11
- Reactivity:
- Mouse
- Mouse
- Mouse
- Host:
- Armenian hamster
- Armenian hamster
- Armenian hamster
- Gene ID:
- 12501
- 12501
- 12501
- Isotype:
- IgG
- IgG
- IgG
- Western blot:
- Yes
- Yes
- Yes
- ImmunoChemistry:
- Yes
- Yes
- Yes
- ImmunoPrecipitation:
- Yes
- Yes
- Yes
- ImmunoFluorescence:
- Yes
- Yes
- Yes
- Flow cytometry:
- Yes
- Yes
- Yes
- Cross adsorption:
- none
- none
- none
- Storage temperature:
- Cool
- Cool
- Cool
- Shipping temperature:
- Ice
- Ice
- Ice
Specifications
Product Information
- Catalog #Supplier #PkAvailabilityPrice
- 35-0031-U10035-0031-U100100 µG1 * 100 µG203 zł
Specifications
Antigen symbolCD3EAntigen nameCD3 Molecule EpsilonEnvironmentally PreferableAntigen synonymsCD3e antigen|TCRE|epsilon subunit of T3|epsilon polypeptide TiT3 complex|T3E|FLJ18683|CD3-epsilon|T-cell surface glycoprotein CD3 epsilon chain|T-cell antigen receptor complex|T-cell surface antigen T3/Leu-4 epsilon chainAntibody typePrimaryClonalityMonoclonalConjugationFITC (Fluorescein Isothiocyanate)Clone145-2C11ReactivityMouseHostArmenian hamsterGene ID12501IsotypeIgGWestern blotYesImmunoChemistryYesImmunoPrecipitationYesImmunoFluorescenceYesFlow cytometryYesCross adsorptionnoneStorage temperatureCoolShipping temperatureIce - 35-0031-U50035-0031-U500500 µG1 * 500 µG502 zł
Specifications
Antigen symbolCD3EAntigen nameCD3 Molecule EpsilonEnvironmentally PreferableAntigen synonymsCD3e antigen|TCRE|epsilon subunit of T3|epsilon polypeptide TiT3 complex|T3E|FLJ18683|CD3-epsilon|T-cell surface glycoprotein CD3 epsilon chain|T-cell antigen receptor complex|T-cell surface antigen T3/Leu-4 epsilon chainAntibody typePrimaryClonalityMonoclonalConjugationFITC (Fluorescein Isothiocyanate)Clone145-2C11ReactivityMouseHostArmenian hamsterGene ID12501IsotypeIgGWestern blotYesImmunoChemistryYesImmunoPrecipitationYesImmunoFluorescenceYesFlow cytometryYesCross adsorptionnoneStorage temperatureCoolShipping temperatureIce - 35-0031-U02535-0031-U02525 µG1 * 25 µG90,80 zł
Specifications
Antigen symbolCD3EAntigen nameCD3 Molecule EpsilonEnvironmentally PreferableAntigen synonymsCD3e antigen|TCRE|epsilon subunit of T3|epsilon polypeptide TiT3 complex|T3E|FLJ18683|CD3-epsilon|T-cell surface glycoprotein CD3 epsilon chain|T-cell antigen receptor complex|T-cell surface antigen T3/Leu-4 epsilon chainAntibody typePrimaryClonalityMonoclonalConjugationFITC (Fluorescein Isothiocyanate)Clone145-2C11ReactivityMouseHostArmenian hamsterGene ID12501IsotypeIgGWestern blotYesImmunoChemistryYesImmunoPrecipitationYesImmunoFluorescenceYesFlow cytometryYesCross adsorptionnoneStorage temperatureCoolShipping temperatureIce