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Anti-APOB Mouse Monoclonal Antibody [clone: F2C3]

Dostawca: Thermo Scientific
MA5-14724 targets Apolipoprotein B in ELISA, IP, and RIA applications and shows reactivity with Human samples. The MA5-14724 immunogen is purified human serum LDL. MA5-14724 detects Apolipoprotein B which has a predicted molecular weight of approximately 513 kDa. Product MA514724 is a smaller package size of MIA1605 (formerly sold as a Seradyn product). This gene product is the main apolipoprotein of chylomicrons and low density lipoproteins. It occurs in plasma as two main isoforms, apoB-48 and apoB-100: the former is synthesized exclusively in the gut and the latter in the liver. The intestinal and the hepatic forms of apoB are encoded by a single gene from a single, very long mRNA. The two isoforms share a common N-terminal sequence. The shorter apoB-48 protein is produced after RNA editing of the apoB-100 transcript at residue 2180 (CAA->UAA), resulting in the creation of a stop codon, and early translation termination. Mutations in this gene or its regulatory region cause hypobetalipoproteinemia, normotriglyceridemic hypobetalipoproteinemia, and hypercholesterolemia due to ligand-defective apoB, diseases affecting plasma cholesterol and apoB levels.

Type: Primary
Antigen: APOB
Clonality: Monoclonal
Clone: F2C3
Conjugation: Unconjugated
Epitope:
Host: Mouse
Isotype: IgG2b
Reactivity: Human



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ZAMÓW

Rozwiń / Zwiń
Rozmiar Ilość Numer katalogowy VWR Ilość
100 ug 100 µG PIEAMA514724 Blocked
Blocked Ten produkt jest zablokowany. Prosimy, skontaktuj się z Działem Obsługi Klienta, aby uzyskać więcej informacji.
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SPECYFIKACJE

Antigen symbol APOB
Antigen name Apolipoprotein B
Reactivity Human
Conjugation Unconjugated
Clonality Monoclonal
Antibody type Primary
Clone F2C3
Host Mouse
Isotype IgG2b
ELISA Yes
ImmunoChemistry Yes
ImmunoPrecipitation Yes
Antigen synonyms apolipoprotein B46, apoB-48, apo B-100, apolipoprotein B-100, apoB-100
Gene ID 338
Stężenie 1 mg/ml
Immunogen Purified human serum LDL
Purification Ion-exchange chromatography
Form Liquid
Storage Buffer 0.01M potassium phosphate, 2.5mM KCl, 1mg/ml BSA, 0.135M NaCl, 0.05% sodium azide
Temperatura przechowywania Maintain refrigerated at 2-8°C for up to 6 months. For long term storage store at -20°C
Shipping Temperature Ice
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