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Anti-BCL10 Mouse Monoclonal Antibody [clone: 4F8]

Dostawca: Thermo Scientific
MA5-14756 targets BCL-10 in FACS, IF, IHC, and WB applications and shows reactivity with Human and mouse samples. The MA5-14756 immunogen is purified recombinant fragment of human BCL-10 expressed in E. Coli. MA5-14756 detects BCL-10 which has a predicted molecular weight of approximately 26kDa. This gene was identified by its translocation in a case of mucosa-associated lymphoid tissue lymphoma. The protein encoded by this gene contains a caspase recruitment domain , and has been shown to induce apoptosis and to activate NF-kappaB. This protein is reported to interact with other CARD domain containing proteins including CARD9, 10, 11 and 14, which are thought to function as upstream regulators in NF-kappaB signaling. This protein is found to form a complex with MALT1, a protein encoded by another gene known to be translocated in MALT lymphoma. MALT1 and this protein are thought to synergize in the activation of NF-kappaB, and the deregulation of either of them may contribute to the same pathogenetic process that leads to the malignancy.

Type: Primary
Antigen: BCL10
Clonality: Monoclonal
Clone: 4F8
Conjugation: Unconjugated
Epitope:
Host: Mouse
Isotype: IgG1
Reactivity: Human, Mouse



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ZAMÓW

Rozwiń / Zwiń
Rozmiar Ilość Numer katalogowy VWR Ilość
100 µg 100 µG PIEAMA514756 Blocked
Blocked Ten produkt jest zablokowany. Prosimy, skontaktuj się z Działem Obsługi Klienta, aby uzyskać więcej informacji.
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SPECYFIKACJE

Antigen symbol BCL10
Antigen name B-cell lymphoma/leukemia 10
Reactivity Human, Mouse
Conjugation Unconjugated
Clonality Monoclonal
Antibody type Primary
Clone 4F8
Host Mouse
Isotype IgG1
Western Blot Yes
ImmunoChemistry Yes
ImmunoFluorescence Yes
Flow Cytometry Yes
Antigen synonyms BCL10, CARMEN, mE10, CIPER, c-E10, CLAP
Gene ID 8915, 12042
Stężenie 1 mg/ml
Immunogen Purified recombinant fragment of human BCL-10 expressed in E. Coli.
Purification purified
Form Liquid
Storage Buffer PBS, 0.03% sodium azide
Temperatura przechowywania Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Shipping Temperature Ice
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