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Anti-TRIM5A Mouse Monoclonal Antibody [clone: 3B11H2]

Dostawca: Thermo Scientific
MA5-15232 targets Trim5a in IHC and WB applications and shows reactivity with Human samples. The MA5-15232 immunogen is purified recombinant fragment of human trim5 alpha expressed in E. Coli. TRIM5-alpha is a protein that is found in the cells of many mammals and fends of various retrovirus infections. It protects monkeys from infection with HIV-1, and humans from infection with some other viruses. If a retrovirus has entered a cell, it needs to shed its capsid in order to reversely transcribe its genes, so that they can be expressed by the host cell. It is believed that TRIM5 alpha, which is present in the cytoplasm, somehow recognizes the capsid and blocks its shedding, thereby stopping the virus in its tracks. It thus represents an intracellular defense completely separate from the rest of the body's immune system.

Type: Primary
Antigen: TRIM5A
Clonality: Monoclonal
Clone: 3B11H2
Conjugation: Unconjugated
Epitope:
Host: Mouse
Isotype: IgG1
Reactivity: Human



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ZAMÓW

Rozwiń / Zwiń
Rozmiar Ilość Numer katalogowy VWR Ilość
100 µL 100 µl PIEAMA515232 Blocked
Blocked Ten produkt jest zablokowany. Prosimy, skontaktuj się z Działem Obsługi Klienta, aby uzyskać więcej informacji.
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SPECYFIKACJE

Antigen symbol TRIM5A
Antigen name Tripartite Motif Containing 5A
Reactivity Human
Conjugation Unconjugated
Clonality Monoclonal
Antibody type Primary
Clone 3B11H2
Host Mouse
Isotype IgG1
Western Blot Yes
ImmunoChemistry Yes
Antigen synonyms RNF88, TRIM5alpha, TRIM5
Gene ID 85363
Format ascites
Immunogen Purified recombinant fragment of human trim5 alpha expressed in E. Coli.
Form Liquid
Storage Buffer ascites, 0.03% sodium azide
Temperatura przechowywania Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Shipping Temperature Ice
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