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Anti-ZAP70 Mouse Monoclonal Antibody [clone: 3D2A4]

Dostawca: Thermo Scientific
MA5-15281 targets ZAP70 in IHC and WB applications and shows reactivity with Human samples. The MA5-15281 immunogen is purified recombinant fragment of human ZAP70 expressed in E. Coli. MA5-15281 detects ZAP70 which has a predicted molecular weight of approximately 70kDa. This gene encodes an enzyme belonging to the protein tyrosine kinase family, and it plays a role in T-cell development and lymphocyte activation. This enzyme, which is phosphorylated on tyrosine residues upon T-cell antigen receptor stimulation, functions in the initial step of TCR-mediated signal transduction in combination with the Src family kinases, Lck and Fyn. This enzyme is also essential for thymocyte development. Mutations in this gene cause selective T-cell defect, a severe combined immunodeficiency disease characterized by a selective absence of CD8-positive T-cells. Two transcript variants that encode different isoforms have been found for this gene.

Type: Primary
Antigen: ZAP70
Clonality: Monoclonal
Clone: 3D2A4
Conjugation: Unconjugated
Epitope:
Host: Mouse
Isotype: IgG1
Reactivity: Human



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ZAMÓW

Rozwiń / Zwiń
Rozmiar Ilość Numer katalogowy VWR Ilość
100 µL 100 µl PIEAMA515281 Blocked
Blocked Ten produkt jest zablokowany. Prosimy, skontaktuj się z Działem Obsługi Klienta, aby uzyskać więcej informacji.
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SPECYFIKACJE

Antigen symbol ZAP70
Antigen name Zeta-chain (TCR) associated protein kinase 70kDa
Reactivity Human
Conjugation Unconjugated
Clonality Monoclonal
Antibody type Primary
Clone 3D2A4
Host Mouse
Isotype IgG1
Western Blot Yes
ImmunoChemistry Yes
Antigen synonyms FLJ17679, STD, TZK, FLJ17670, SRK, ZAP70
Gene ID 7535
Format ascites
Immunogen Purified recombinant fragment of human ZAP70 expressed in E. Coli.
Form Liquid
Storage Buffer ascites, 0.03% sodium azide
Temperatura przechowywania Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Shipping Temperature Ice
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