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Anti-EPHA2 Mouse Monoclonal Antibody [clone: 1B3C7]

Dostawca: Thermo Scientific
MA5-15284 targets EphA2 in IHC and WB applications and shows reactivity with Human samples. The MA5-15284 immunogen is purified recombinant fragment of EphA2 expressed in E. Coli. EPH receptor A2 (EphA2), with 976-amino acid protein (about 107 kDa), belongs to the ephrin receptor subfamily of the protein-tyrosine kinase family. EphA1, EphA2, EphA3, EphA4, EphA5, EphA6, EphA7, EphA8, EphA10, EphB1, EphB2, EphB3, EphB4 and EphB6 are Eph family receptors for Ephrin family ligands. In normal cells, EphA2 negatively regulates cell growth and invasiveness. EphA2 is overexpressed by many human cancers, and is often associated with poor prognostic features. The clinical significance of the expression of EphA2 was observed in breast, prostate, colon, skin, cervical, ovarian, and lung cancers.EphA2 may serve as a novel target for bladder cancer, colonic adenocarcinoma and ovarian cancer therapy.

Type: Primary
Antigen: EPHA2
Clonality: Monoclonal
Clone: 1B3C7
Conjugation: Unconjugated
Host: Mouse
Isotype: IgM
Reactivity: Human, Mouse



Rozwiń / Zwiń
Rozmiar Ilość Numer katalogowy VWR Ilość
100 µL 100 µl PIEAMA515284 Blocked
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Antigen symbol EPHA2
Antigen name Ephrin type A receptor 2
Reactivity Human, Mouse
Conjugation Unconjugated
Clonality Monoclonal
Antibody type Primary
Clone 1B3C7
Host Mouse
Isotype IgM
Western blot Yes
ImmunoChemistry Yes
Antigen synonyms ECK, EPHA2
Gene ID 1969, 13836
Format ascites
Immunogen Purified recombinant fragment of EphA2 expressed in E. Coli.
Form Liquid
Storage buffer ascites, 0.03% sodium azide
Temperatura przechowywania Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Shipping temperature Ice
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