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Anti-Dynamin-1 Mouse Monoclonal Antibody [clone: 3G4B6]

Dostawca: Thermo Fisher Scientific
PIEAMA515285EA 0 PLN
PIEAMA515285
Anti-Dynamin-1 Mouse Monoclonal Antibody [clone: 3G4B6]
Przeciwciała
MA5-15285 targets Dynamin-1 in IHC and WB applications and shows reactivity with Human samples. The MA5-15285 immunogen is purified recombinant fragment of human Dynamin-1 expressed in E. Coli. MA5-15285 detects Dynamin-1 which has a predicted molecular weight of approximately 97kDa. Dynamin-1 (Dyn1), with 864-amino acid protein (about 95kDa), belongs to the dynamin family. Dynamin-1 (neuron-specific), dynamin-2 (ubiquitously expressed), and dynamin-3 (expressed only in the testis, brain, and lung), constitute the dynamin family. Members of the dynamin family are GPTase, microtubule-associated proteins which are involved in endocytosis, synaptic transmission and neurogenesis. Dynamin-1 is phosphorylated in nerve terminals exclusively in the cytosolic compartment and in vitro by protein kinase C. Dynamin-1 is a large GTPase enzyme required in membrane constriction and fission during multiple forms of endocytosis. Dynamin-1 is also a key molecule required for the recycling of synaptic vesicles in neurons, and it has been known that dynamin-1 gene expression is induced during neuronal differentiation.

Type: Primary
Antigen: Dynamin-1
Clonality: Monoclonal
Clone: 3G4B6
Conjugation: Unconjugated
Epitope:
Host: Mouse
Isotype: IgG2a
Reactivity: Mouse, Rat, Human
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