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Anti-Dynamin-1 Mouse Monoclonal Antibody [clone: 3G4B6]

Dostawca: Thermo Scientific
MA5-15285 targets Dynamin-1 in IHC and WB applications and shows reactivity with Human samples. The MA5-15285 immunogen is purified recombinant fragment of human Dynamin-1 expressed in E. Coli. MA5-15285 detects Dynamin-1 which has a predicted molecular weight of approximately 97kDa. Dynamin-1 (Dyn1), with 864-amino acid protein (about 95kDa), belongs to the dynamin family. Dynamin-1 (neuron-specific), dynamin-2 (ubiquitously expressed), and dynamin-3 (expressed only in the testis, brain, and lung), constitute the dynamin family. Members of the dynamin family are GPTase, microtubule-associated proteins which are involved in endocytosis, synaptic transmission and neurogenesis. Dynamin-1 is phosphorylated in nerve terminals exclusively in the cytosolic compartment and in vitro by protein kinase C. Dynamin-1 is a large GTPase enzyme required in membrane constriction and fission during multiple forms of endocytosis. Dynamin-1 is also a key molecule required for the recycling of synaptic vesicles in neurons, and it has been known that dynamin-1 gene expression is induced during neuronal differentiation.

Type: Primary
Antigen: Dynamin-1
Clonality: Monoclonal
Clone: 3G4B6
Conjugation: Unconjugated
Host: Mouse
Isotype: IgG2a
Reactivity: Mouse, Rat, Human



Rozwiń / Zwiń
Rozmiar Ilość Numer katalogowy VWR Ilość
100 µL 100 µl PIEAMA515285 Blocked
Blocked Ten produkt jest zablokowany. Prosimy, skontaktuj się z Działem Obsługi Klienta, aby uzyskać więcej informacji.
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Antigen symbol Dynamin-1
Antigen name Dynamin-1
Reactivity Mouse, Human, Rat
Conjugation Unconjugated
Clonality Monoclonal
Antibody type Primary
Clone 3G4B6
Host Mouse
Isotype IgG2a
Western blot Yes
ImmunoChemistry Yes
Antigen synonyms DNM1, DNM
Gene ID 13429, 140694, 1759
Format ascites
Immunogen Purified recombinant fragment of human Dynamin-1 expressed in E. Coli.
Form Liquid
Storage buffer ascites, 0.03% sodium azide
Temperatura przechowywania Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Shipping temperature Ice
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