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Anti-LCK Mouse Monoclonal Antibody [clone: 8E5F9, 4B2C7]

Dostawca: Thermo Scientific
MA5-15295 targets Lck in WB applications and shows reactivity with Human samples. The MA5-15295 immunogen is purified recombinant fragment of human Lck expressed in E. Coli. MA5-15295 detects Lck which has a predicted molecular weight of approximately 56kDa. This gene is a member of the Src family of protein tyrosine kinases . The encoded protein is a key signaling molecule in the selection and maturation of developing T-cells. It contains N-terminal sites for myristylation and palmitylation, a PTK domain, and SH2 and SH3 domains which are involved in mediating protein-protein interactions with phosphotyrosine-containing and proline-rich motifs, respectively. The protein localizes to the plasma membrane and pericentrosomal vesicles, and binds to cell surface receptors, including CD4 and CD8, and other signaling molecules. Multiple alternatively spliced variants, encoding the same protein, have been described.

Type: Primary
Antigen: LCK
Clonality: Monoclonal
Clone: 8E5F9, 4B2C7
Conjugation: Unconjugated
Epitope:
Host: Mouse
Isotype: IgG2a
Reactivity: Human



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ZAMÓW

Rozwiń / Zwiń
Rozmiar Ilość Numer katalogowy VWR Ilość
100 µL 100 µl PIEAMA515295 Blocked
Blocked Ten produkt jest zablokowany. Prosimy, skontaktuj się z Działem Obsługi Klienta, aby uzyskać więcej informacji.
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SPECYFIKACJE

Antigen symbol LCK
Antigen name Lymphocyte-specific Protein tyrosine kinase
Reactivity Human
Conjugation Unconjugated
Clonality Monoclonal
Antibody type Primary
Clone 8E5F9, 4B2C7
Host Mouse
Isotype IgG2a
Western Blot Yes
Antigen synonyms pp58lck, LCK, p56lck, YT16
Gene ID 3932
Format ascites
Immunogen Purified recombinant fragment of human Lck expressed in E. Coli.
Form Liquid
Storage Buffer ascites, 0.03% sodium azide
Temperatura przechowywania Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Shipping Temperature Ice
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