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Anti-SR-BI Rabbit Polyclonal Antibody

Dostawca: Thermo Fisher Scientific
PIEAPA116788EA 0 PLN
PIEAPA116788
Anti-SR-BI Rabbit Polyclonal Antibody
Przeciwciała
Suggested positive control: antigen standard for SCARB1 (transient overexpression lysate). High density lipoproteins (HDLs) play a critical role in cholesterol metabolism and their plasma concentrations are inversely correlated with risk for atherosclerosis. The SR-BI binds HDLs and mediates selective uptake of HDL cholesteryl ester. SR-BI binds HDL with high affinity, is expressed primarily in liver and nonplacental steroidgenic tissues, and mediates selective cholesterol uptake by a distinct mechanism. In mice, it seems that SR-BI plays a key role in determining the levels of plasma lipoprotein cholesterol and the accumulation of cholesterol stores in the adrenal gland.

Type: Primary
Antigen: SR-BI
Clonality: Polyclonal
Clone:
Conjugation: Unconjugated
Epitope:
Host: Rabbit
Isotype: IgG
Reactivity: Mouse, Rabbit, Primates, Rat, Mink, Human, Hamster
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