This MAb recognizes an extracellular epitope of an integral membrane glycoprotein of 150 kDa, identified as CD13. This antigen is present on most cells of myeloid origin including granulocytes, monocytes, mast cells, and GM-progenitor cells. It is also expressed by the majority of AML, CML in myeloid blast crisis, and in a smaller fraction of lymphoid leukemias. It is absent from normal lymphocytes, platelets and erythrocytes. CD13 is also present on fibroblasts; endothelial cells, epithelial cells from renal proximal tubules and intestinal brush border, bone marrow stromal cells, osteoclasts, and cells lining bile duct canaliculi. CD13 is identical to aminopeptidase N (APN), a prominent membrane-bound metalloprotease present on the surface of intestinal brush border and renal tubules. CD13 plays a role in metabolism of biologically active peptides, in phagocytosis, and in bactericidal/tumoricidal activities. It also serves as a receptor for human coronaviruses (HCV). The lineage-restricted pattern of expression of CD13 within the hemopoietic compartment suggests that it may be important in myeloid cell differentiation.
Type: Primary
Antigen: ANPEP
Clonality: Monoclonal
Clone: APN/514
Conjugation: CF405S
Epitope:
Host: Mouse
Isotype: IgG1 kappa
Reactivity: Human
Specifications
- Catalog No:
- BNC040514-100
- BNC040514-500
- Antigen symbol:
- ANPEP
- ANPEP
- Antigen name:
- CD13
- CD13
- Antigen synonyms:
- ANPEP|PEPN|Microsomal aminopeptidase|Lap1|p150|gp150|APN|Aminopeptidase N|hAPN|Aminopeptidase M|Alanyl aminopeptidase|AP-M|Myeloid plasma membrane glycoprotein CD13
- ANPEP|PEPN|Microsomal aminopeptidase|Lap1|p150|gp150|APN|Aminopeptidase N|hAPN|Aminopeptidase M|Alanyl aminopeptidase|AP-M|Myeloid plasma membrane glycoprotein CD13
- Antibody type:
- Primary
- Primary
- Clonality:
- Monoclonal
- Monoclonal
- Conjugation:
- CF® 405S
- CF® 405S
- Clone:
- Clone APN/514
- Clone APN/514
- Reactivity:
- Human
- Human
- Host:
- Mouse
- Mouse
- Gene ID:
- 1239
- 1239
- Isotype:
- IgG1 kappa
- IgG1 kappa
- ImmunoChemistry:
- Yes
- Yes
- ImmunoFluorescence:
- Yes
- Yes
- Concentration:
- 0,1 mg/ml
- 0,1 mg/ml
- Storage buffer:
- PBS/0,1% BSA/0,05% azide
- PBS/0,1% BSA/0,05% azide
Specifications
Product Information
- Catalog #Supplier #SizePkAvailabilityPrice
- BNC040514-100BNC040514-100100 μL100 µl1 * 100 µl1 040 zł
Specifications
Antigen symbolANPEPAntigen nameCD13Environmentally PreferableAntigen synonymsANPEP|PEPN|Microsomal aminopeptidase|Lap1|p150|gp150|APN|Aminopeptidase N|hAPN|Aminopeptidase M|Alanyl aminopeptidase|AP-M|Myeloid plasma membrane glycoprotein CD13Antibody typePrimaryClonalityMonoclonalConjugationCF® 405SCloneClone APN/514ReactivityHumanHostMouseGene ID1239IsotypeIgG1 kappaImmunoChemistryYesImmunoFluorescenceYesConcentration0,1 mg/mlStorage bufferPBS/0,1% BSA/0,05% azide - BNC040514-500BNC040514-500500 μL500 µl1 * 500 µl2 860 zł
Specifications
Antigen symbolANPEPAntigen nameCD13Environmentally PreferableAntigen synonymsANPEP|PEPN|Microsomal aminopeptidase|Lap1|p150|gp150|APN|Aminopeptidase N|hAPN|Aminopeptidase M|Alanyl aminopeptidase|AP-M|Myeloid plasma membrane glycoprotein CD13Antibody typePrimaryClonalityMonoclonalConjugationCF® 405SCloneClone APN/514ReactivityHumanHostMouseGene ID1239IsotypeIgG1 kappaImmunoChemistryYesImmunoFluorescenceYesConcentration0,1 mg/mlStorage bufferPBS/0,1% BSA/0,05% azide