About this item
Reacts with a common epitope of human major histocompatibility (MHC) class II antigens, HLA-DR and DP. Human MHC class II antigens are transmembrane glycoproteins composed of an chain (36 kDa) and a chain (27 kDa). They are expressed primarily on antigen presenting cells such as B lymphocytes, monocytes, macrophages, and thymic epithelial cells and are also present on activated T lymphocytes. Human MHC class II genes are located in the HLA-D region that encodes at least six and ten chain genes. Three loci, DR, DQ and DP, encode the major expressed products of the human class II region. The human MHC class II molecules bind intracellularly processed peptides and present them to T-helper cells. They, therefore, have a critical role in the initiation of the immune response. It has been shown that some autoimmune diseases are associated with certain class II alleles.
Type: Primary
Antigen: HLA-DPB1 & HLA-DRA
Clonality: Monoclonal
Clone: Bra-14
Conjugation: CF488A
Epitope:
Host: Mouse
Isotype: IgG3 kappa
Reactivity: Human
Specifications
- Catalog No:
- BNC881129-100
- BNC881129-500
- Antigen symbol:
- MHC2
- MHC2
- Antigen name:
- MHC II
- MHC II
- Antigen synonyms:
- HLA-DRA|HLA-DPB1
- HLA-DRA|HLA-DPB1
- Antibody type:
- Primary
- Primary
- Clonality:
- Monoclonal
- Monoclonal
- Conjugation:
- CF® 488A
- CF® 488A
- Clone:
- Clone Bra-14
- Clone Bra-14
- Reactivity:
- Human
- Human
- Host:
- Mouse
- Mouse
- Gene ID:
- 347270 (HLA-DP) , 520048 (HLA-DR)
- 347270 (HLA-DP) , 520048 (HLA-DR)
- Isotype:
- IgG3 kappa
- IgG3 kappa
- ImmunoChemistry:
- Yes
- Yes
- ImmunoFluorescence:
- Yes
- Yes
- Concentration:
- 0,1 mg/ml
- 0,1 mg/ml
- Storage buffer:
- PBS/0,1% BSA/0,05% azide
- PBS/0,1% BSA/0,05% azide
Specifications
Product Information
- Catalog #Supplier #SizePkAvailabilityPrice
- Specifications:
More
Specifications
Antigen symbolMHC2Antigen nameMHC IIEnvironmentally PreferableAntigen synonymsHLA-DRA|HLA-DPB1Antibody typePrimaryClonalityMonoclonalConjugationCF® 488ACloneClone Bra-14ReactivityHumanHostMouseGene ID347270 (HLA-DP) , 520048 (HLA-DR)IsotypeIgG3 kappaImmunoChemistryYesImmunoFluorescenceYesConcentration0,1 mg/mlStorage bufferPBS/0,1% BSA/0,05% azide - Specifications:
More
Specifications
Antigen symbolMHC2Antigen nameMHC IIEnvironmentally PreferableAntigen synonymsHLA-DRA|HLA-DPB1Antibody typePrimaryClonalityMonoclonalConjugationCF® 488ACloneClone Bra-14ReactivityHumanHostMouseGene ID347270 (HLA-DP) , 520048 (HLA-DR)IsotypeIgG3 kappaImmunoChemistryYesImmunoFluorescenceYesConcentration0,1 mg/mlStorage bufferPBS/0,1% BSA/0,05% azide