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Anti-DAPK2 Rabbit Polyclonal Antibody (Cy5.5®)

Dostawca: Bioss
BOSSBS-1713R-CY5.5EA 4310 PLN
BOSSBS-1713R-CY5.5
Anti-DAPK2 Rabbit Polyclonal Antibody (Cy5.5®)
Przeciwciała
Calcium/calmodulin-dependent serine/threonine kinase involved in multiple cellular signaling pathways that trigger cell survival, apoptosis, and autophagy. Regulates both type I apoptotic and type II autophagic cell deaths signal, depending on the cellular setting. The former is caspase-dependent, while the latter is caspase-independent and is characterized by the accumulation of autophagic vesicles. Acts as a mediator of anoikis and a suppressor of beta-catenin-dependent anchorage-independent growth of malignant epithelial cells. May play a role in granulocytic maturation. Isoform 2 is not regulated by calmodulin. It can phosphorylate MYL9. It can induce membrane blebbing and autophagic cell death.

Recommended Dilutions: IF(IHC-P): 1:50-200

Type: Primary
Antigen: DAPK2
Clonality: Polyclonal
Clone:
Conjugation: Cy5.5®
Epitope:
Host: Rabbit
Isotype: IgG
Reactivity: Human, Mouse, Rat
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