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Anti-SPTLC2 Rabbit Polyclonal Antibody

Dostawca: ProSci Inc.
SPTLC2 is a long chain base subunit of serine palmitoyltransferase. Serine palmitoyltransferase, which consists of two different subunits, is the key enzyme in sphingolipid biosynthesis. It catalyzes the pyridoxal-5-prime-phosphate-dependent condensation of L-serine and palmitoyl-CoA to 3-oxosphinganine. Mutations in this gene were identified in patients with hereditary sensory neuropathy type I.This gene encodes a long chain base subunit of serine palmitoyltransferase. Serine palmitoyltransferase, which consists of two different subunits, is the key enzyme in sphingolipid biosynthesis. It catalyzes the pyridoxal-5-prime-phosphate-dependent condensation of L-serine and palmitoyl-CoA to 3-oxosphinganine. Mutations in this gene were identified in patients with hereditary sensory neuropathy type I. Alternatively spliced variants encoding different isoforms have been identified.

SPTLC2 antibody can be used for detection of SPTLC2 by ELISA at 1:312500. SPTLC2 antibody can be used for detection of SPTLC2 by western blot at 1 μg/mL, and HRP conjugated secondary antibody should be diluted 1:50,000 - 100,000.

Antibody is purified by peptide affinity chromatography method.

Antibody is lyophilized in PBS buffer with 2% sucrose. Add 50 μL of distilled water. Final antibody concentration is 1 mg/mL.

Aliquot and store at -20°C or below. Avoid multiple freeze-thaw cycles.

Type:
Antigen: SPTLC2
Clonality: Polyclonal
Clone:
Conjugation: Unconjugated
Epitope:
Host: Rabbit
Isotype:
Reactivity: Human, Mouse, Rat




 

ZAMÓW

Rozwiń / Zwiń
Rozmiar Ilość Numer katalogowy VWR Ilość
50 µg 50 µG PRSI26-333
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SPECYFIKACJE

Antigen symbol SPTLC2
Antigen name Serine Palmitoyltransferase, Long Chain Base Subunit 2
Reactivity Mouse, Rat, Human
Conjugation Unconjugated
Clonality Polyclonal
Host Rabbit
Western blot Yes
ELISA Yes
Antigen synonyms LCB2, KIAA0526, Long chain base biosynthesis protein 2, hLCB2a, Serine palmitoyltransferase 2, SPT2, LCB2A, NSAN1C, HSN1C, LCB 2
Immunogen A synthetic peptide corresponding a region of human SPTLC2.
Form Lyophilized
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