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DMNPE-caged Luciferin

Dostawca: OZ BIOSCIENCES

OZBILC50000EA 3550 PLN
OZBILC50000 OZBILC25000 OZBILC10000
DMNPE-caged Luciferin
DMNPE-caged Luciferin

DMNPE-caged luciferin is a bioluminescent luciferase substrate used to measure intracellular functions since it readily crosses cell membranes. It is a D-luciferin ester analogue of luciferin.


  • High purity
  • Cell permeable, efficient luciferin delivery into intact cells, even at neutral pH
  • Ideal for in vivo and in vitro applications
  • Induces prolonged release of luciferin by the action of cells esterases
  • Allows to follow changes in gene expression in live cells


Once the caged luciferin is inside the cells, active luciferin can be released by the action of endogenous intracellular esterases or by a flash of UV light. This implies:
1. A more efficient delivery of luciferin into intact living cells and improved sensitivity analysis of in vivo luciferase assays.
2. A long-term measurement of luciferase activity since hydrolysis by esterases allows a continuous supply of active Luciferin.


DMNPE-caged luciferin is a good alternative to D-Luciferin classically used to measure luciferase activity in live cells. Indeed, the difficulty to deliver D-luciferin into living cells renders in vivo quantification limited to a certain extent - for example, permeability issues at neutral pH.


Suitable for whole animal imaging, reporter gene assays, ATP assays, pyrosequencing and luciferase fragment complementation.


Sposób pakowania: Packed in an amber bottle under nitrogen.

Formuła: C₂₁H₁₉N₃O₇S₂
MW: 489,52 g/mol
Numer CAS: 223920-67-0

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