Collagen I is found in most tissues and organs, but is most plentiful in dermis, tendon, and bone. Used as a thin coating in cell and tissue culture, it is often used to enhance cell attachment and proliferation. When applied as a gel it can be used to promote expression of cell-specific morphology and function. Collagen I is commonly used to culture endothelial cells, hepatocytes, muscle cells, and a variety of other cell types. The HC formulation of rat tail collagen I is used for three dimensional applications requiring a sturdy gel that provides a maximal 3D support matrix (guidelines are included with product).
Quality control: All preparations are quality controlled by SDS-PAGE and tested and found negative for bacteria, fungi, and mycoplasma. Source material for human collagen I tested for hepatitis B antigen and HIV-1 antibody.